Listed below are clinical trials that have opened at SCCA in the last several weeks. These trials are looking at new treatments for adult patients with bladder cancer, breast cancer, prostate cancer, chronic lymphocytic leukemia, gynecologic cancer and screening Barrett’s esophagus. Check out our website to learn about the more than 200 ongoing clinical trials at SCCA, and follow us on Twitter at @SCCA_Trials for information about recently opened trials.
Ramucirumab (LY3009806) plus Docetaxel for Urothelial Cancer (20150398)
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Ramucirumab plus Docetaxel Versus Placebo plus Docetaxel in Patients with Locally Advanced or Unresectable or Metastatic Urothelial Carcinoma Who Progressed on or After Platinum-Based Therapy (RANGE)
Margetuximab plus Chemotherapy vs. Trastuzumab plus Chemotherapy for HER2+ Metastatic Breast Cancer (20151845)
A Phase 3, Randomized Study of Margetuximab Plus Chemotherapy vs Trastuzumab Plus Chemotherapy in the Treatment of Patients with HER2+ Metastatic Breast Cancer Who Have Received Two Prior Anti-HER2 Therapies and Require Systemic Treatment
Obinutuzumab + Chlorambucil vs. ACP-196 + Obinutuzumab for Chronic Lymphocytic Leukemia (9428)
A Randomized, Multicenter, Open-Label, 3 Arm Phase 3 Study of Obinutuzumab in Combination with Chlorambucil, ACP-196 in Combination with Obinutuzumab, and ACP-196 Monotherapy in Subjects with Previously Untreated Chronic Lymphocytic Leukemia.
Enzalutamide and Cabazitaxel for Metastatic, Hormone-Resistant Prostate Cancer (9279)
A Phase I/II Trial of Concurrent Chemohormonal therapy using Enzalutamide (MDV-3100) and Cabazitaxel in Patients with Metastatic Castration Resistant Prostate Cancer
Combination of Cediranib and Olaparib Compared to Cediranib or Olaparib Alone, or Standard Chemotherapy for Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (NRG-GY005)
A Randomized Phase II/III Study of the Combination of Cediranib and Olaparib Compared to Cediranib or Olaparib Alone, or Standard of Care Chemotherapy in Women with Recurrent Platinum-Resistant or -Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (COCOS)
Tethered Capsule Endoscope in Screening for Barrett’s Esophagus (9561)
Tethered Capsule Endoscope in Screening for Barrett’s Esophagus – A Pilot Study